Jack Bauer endures the elements and fights on to prevent an attack that could change the country forever; as the catastrophic blow to the nation nears, Tony Almeida operates from the field, and Jack's daughter Kim returns; the stakes are raised when the administration is faced with a blackmail scenario.

曾受生化物感染的Jack終病發，病癥逐漸出現，但醫生卻無計可施。縱然如此，Jack仍堅持戰鬥，預防足以影響國家命運的恐怖襲擊。一場大型災難威脅著國家的安全，Tony以身犯險，執行任務。與此同時，Jack的愛女Kim前來找他，父女終可相見，可是很快便要分離……

在剛公佈的艾美獎得獎名單中，飾演女總統Allison Taylor的Cherry Jones榮獲最佳劇集女配角殊榮。

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